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human breast cancer tissue array  (Novus Biologicals)


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    Novus Biologicals human breast cancer tissue array
    Human Breast Cancer Tissue Array, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 20 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+breast+cancer+tissue/pmc12478062-532-1-9?v=Novus+Biologicals
    Average 93 stars, based on 20 article reviews
    human breast cancer tissue array - by Bioz Stars, 2026-06
    93/100 stars

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    ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
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    ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
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    ARTS is predominantly expressed in resistant <t>breast</t> <t>cancer</t> <t>tissues</t> and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.
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    Image Search Results


    ARTS is predominantly expressed in resistant breast cancer tissues and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.

    Journal: Research

    Article Title: ARTS Confers Chemoresistance of Breast Cancer by Inducing Apoptosis-Dependent Autophagy via Livin–MDM2–p53 Pathway

    doi: 10.34133/research.1086

    Figure Lengend Snippet: ARTS is predominantly expressed in resistant breast cancer tissues and promotes chemoresistance in breast cancer cells. (A) Screening workflow for chemoresistance-related genes in breast cancer. DEGs from GSE288073 are shown in a volcano plot, followed by overlap with apoptosis-related and mitochondria-related gene sets, yielding 12 DEGs; ARTS was prioritized and evaluated by Kaplan–Meier survival analysis for postchemotherapy prognosis. FPKM, fragments per kilobase of transcript per million mapped reads. (B) Representative hematoxylin and eosin (H&E) and IHC images of ARTS in paired pre- and post-NAC samples from NAC-sensitive and NAC-resistant patients. The black arrow indicates a residual small cluster of tumor cells. Scale bar, 50 μm. (C) Association of ARTS protein with MPG score and Ki-67 in pre- and post-NAC samples. (D) Kaplan–Meier analyses of OS and RFS stratified by ARTS protein (low versus high). (E and F) MTT and (G and H) colony formation assays in sh-Ctrl versus sh-ARTS MDA-MB-231 and Flag versus Flag–ARTS MCF-7 cells under the indicated treatments. * P < 0.05; *** P < 0.001. ns, not significant.

    Article Snippet: Human breast cancer tissue samples were obtained from the First Affiliated Hospital of Anhui Medical University (Hefei, Anhui, China).

    Techniques: